What are the effects of hemophilia

The most common cause of disability from hemophilia is chronic joint disease, or arthropathy, which is caused by uncontrolled bleeding into the joints. Hemorrhage, which is a severe internal or external discharge of blood, is a continuing p…

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Hemophilia is caused by a defect in one of the body’s proteins that controls how the blood clots. When it’s not working correctly, it takes longer for the blood to clot. Hemophilia is a condition that is present from birth. People who have …

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The effects of Hemophilia is that the blood does not clot propperly. This is turn can cause bleeding in the joints and muscles.

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What are the effects of hemophilia?

Q: So, does anyone know what are the effects that are caused by this disease?

A: Hemophilia is caused by a defect in one of the body’s proteins that controls how the blood clots. When it’s not working correctly, it takes longer for the blood to clot. Hemophilia is a condition that is present from birth. People who have hemophilia have a delayed clotting time. They bruise easily and may have excessive bleeding after injuries or surgeries or tooth extractions. They may also have oozing from even minor wounds. Symptoms may be mild (only showing after major injuries) or more severe, showing up after very minor injuries. People, especially those who have the more severe forms of hemophilia, often need regular blood infusions of the protein that their body lacks. People with the more mild forms of the condition may only need infusions at the time of injury or surgery. Hemophilia does run in families and primarily affects males. Females are usually “carriers” only, and usually don’t have symptoms. Of females who do have symptoms, they may have heavier menstrual cycles and heavier bleeding after childbirth.

What are the physiological effects of hemophilia and sickle-cell anemia?

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A: Hemophilia means inablility or delayed clot formation.You need clot to stop bleeding from a ruptured capillary.Capillaries rupture even when you clap,sit,bump into something,etc.In severs hemophilia ,even such minor things that normally go unnoticed can cause heavy bleeding.Thus physiological effects are:Hemorrhage-other effects resulting from hemorrhage are1.Anemia due to loss of blood2.Hypovolemic shock3.Hypotension,etcSickle cell anemia-The precipitated hemoglobin released from the hemolysed RBCs increases the viscosity of the blood.This caused sharp increase in blood pressure.The increase may be so sharp that it may damage the endothelium of blood vessels.A clot formed at the site of damaged endothelium may detach and travel in the main blood stream.If the clot becomes too large it could block small bloodvessel and may cause local tissue necrosis.Other effects include those of general anemia like increased erythrpoietin secretion,increased activity of bone marrow,increase in reticulocyte count,etc.

what are the effects of Hemophilia ??

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A: Hemophilia What is Hemophilia?Hemophilia is an inherited bleeding, or coagulation, disorder. Persons with hemophilia lack the ability to stop bleeding because of the low levels, or complete absence, of specific proteins, called ?factors,? in their blood that are necessary for clotting. Proper clotting of blood helps prevent excessive bleeding. There are several types of hemophilias, but the most common and well known include the following: hemophilia A – lack of factor VIII. hemophilia B – lack of factor IX. In the US, there are about 20,000 persons who have hemophilia, and each year approximately 400 babies are born with the disease.What Causes Hemophilia ?Hemophilia types A and B are inherited diseases passed on from a gene located on the X chromosome. Females have two X chromosomes, while males have one X and one Y chromosome. A female carrier of hemophilia has the hemophilia gene on one of her X chromosomes, and there is a 50 percent chance that she may pass the defective gene to her male offspring. Males who inherit the defective gene will develop hemophilia. Males with hemophilia do not pass the gene to their sons; however, they do pass the gene to their daughters. Females who inherit the defective gene will become carriers who may, in turn, have a 50 percent chance of passing it on to their children. Although females who inherit the gene generally have no active problems related to hemophilia, some may have other problems associated with bleeding, such as excessive menstrual bleeding, frequent or severe nosebleeds, or bleeding after dental procedures or surgery. In about one-third of hemophilia cases, there is no family history of the disease. These cases are due to a new or spontaneous development of the defective gene in the female.What are the Symptoms of Hemophilia?The most common symptom of hemophilia is excessive, uncontrollable bleeding because of the missing or low-level clotting factor in the blood. Bleeding may occur even when there is no injury. It most often occurs in the joints and in the head.The following are the other most common symptoms of hemophilia. However, each individual may experience symptoms differently. Symptoms may include: bruisingBruises can occur from small accidents, which can result in a large hematoma (a collection of blood under the skin causing swelling). bleeds easilyA tendency to bleed from the nose, mouth, and gums with minor trauma, teeth brushing, and/or dental work is often an indication of hemophilia.bleeding into a jointHemarthrosis (bleeding into a joint) can cause pain, immobility, and eventually deformity if not medically managed properly. This is the most common site of complications due to hemophilia bleeding. These joint bleeds can lead to chronic, painful, arthritis, deformity, and crippling with repeated occurrences. bleeding into the musclesBleeding into the muscles can cause swelling, pain, and redness. Swelling from excessive blood in these areas can cause increased pressure on tissues and nerves in the area, resulting in permanent damage and/or deformity. bleeding from injury or bleeding in the brainBleeding from injury, or spontaneously in the brain, is the most common cause of death in children with hemophilia and the most serious bleeding complication. other sources of bleedingBlood found in the urine or stool may also be a symptom of hemophilia.The symptoms of hemophilia may resemble other blood disorders or medical problems. Always consult your physician for a diagnosis. How is Hemophilia Diagnosed?In addition to a complete medical history and physical examination, your physician may perform numerous blood tests including clotting factor levels, a complete blood count (CBC), assessment of bleeding times, and/or DNA testing. What are the Effects of Hemophilia?The most common cause of disability from hemophilia is chronic joint disease, or arthropathy, which is caused by uncontrolled bleeding into the joints.Hemorrhage, which is a severe internal or external discharge of blood, is a continuing problem.Treatment for Hemophilia:Specific treatment for hemophilia will be determined by your physician based on: your age, overall health, and medical history extent of the disease type and severity of hemophilia your tolerance for specific medications, procedures, or therapies expectations for the course of the disease your opinion or preference Treatment may include: blood transfusions prophylactic (preventive) treatment with infused clotting factors