What is Asthma?

What is asthma?
Asthma is a disease of the lungs. It is a disease that is much more common than it used to be. It now affects more than 22 million people in the United States- more than twice as many as in the 1980’s. It is one of the most common chronic diseases of childhood. It leads to 500,000 hospital admissions and 5000 deaths every year.

The disease affects the large tubes of the lung called the bronchial tubes. With asthma, the bronchial tubes are hyper responsive causing overreaction to allergens and irritants. This results in the tube lining becoming inflamed and the muscles surrounding the bronchial tubes squeezing the airways, making the passages very narrow and difficult for the air to go through. As the disease persists, the inflammation of the bronchial tube lining becomes worse and worse, leading to increased mucus production and further narrowing of the airways. Over time, without treatment, the damage on the bronchial tubes can become irreversible, leading to a permanent loss of lung function.

What are the symptoms of asthma?
Asthma symptoms vary from person to person. Common symptoms of asthma include:

Shortness of breath, or trouble breathing – It may be a sensation of breathlessness, or not being able to get enough air in or out of your lungs. Chest tightness – It may feel like something is squeezing or sitting on your chest. Wheezing – A high pitched whistling or squeaky sound when you breathe. Coughing – A dry, nonproductive, cough. It is often worse at night or early in the morning.

Symptoms can vary from person to person, and not every asthmatic will have all of those symptoms. Should one or more of the above occur, from mild to extreme, contact your board certified allergist for an evaluation.

What causes asthma?
The exact cause of asthma is unclear. It appears that asthma is the result of a combination of factors, to include genes and environment. Individuals whose parents have asthma have a higher risk of developing asthma themselves, so genes seem to be a factor. One gene that appears to be associated with asthma is called ADAM33. However, asthma also develops in individuals where there is no family of asthma, so genes are not the only factor in asthma.

Allergies play an important role in a large number of asthmatics. It is estimated that asthma is related to allergies in up to 90% of children and 50% of adults. Allergies to dust mites , animals ( cats , dogs ), mold, grasses, and cockroaches have been strongly associated with asthma. Some people have asthma attacks after heavy rains and thunderstorms. This phenomenon, called “thunder-storm asthma” appears to be due to the breaking up of grass pollen (such as rye grass) and mold spores (such as Alternaria ) from the air drops as they hit the surface and the winds which can disperse the pollen over great distances.

In some individuals, genes and allergies do not seem to have an important role in their asthma. In some women, hormones seem to be an important factor. Their asthma can correlate with their menstrual cycle or menopause. In some, pregnancy is associated with a dramatic improvement, or worsening of their asthma.

In up to 10% of asthmatics, aspirin and non steroidal anti-inflammatory (NSAID) medications like ibuprofen (Advil, Motrin) and naproxen (Aleve) can trigger asthma attacks.

Other things that can trigger asthma attacks include infections (such as colds and sinus infections), cigarette smoke, air pollution (including ozone), cold air, strong odors (paint, perfumes…), and sulfites .

Is my asthma under control?
To find out if your asthma is under control, answer these questions:

Have you missed any school or work in the past month due to your asthma? Do you have trouble with exercise/sports because of asthma symptoms (chest tightness, cough, shortness of breath, wheezing)? Do you take the escalator instead of the stairs because you get short of breath? Do you use your rescue inhaler more than 2 times per week? Do you have chest tightness, cough, shortness of breath, or wheezing during the day more than 2 times per week? Do you have chest tightness, cough, shortness of breath, or wheezing at night more than 2 times per month? Do you refill your rescue inhaler more than 2 times per year? Do you avoid the homes of friends with pets because you get shortness of breath, wheezing, or chest tightness?

If you answered yes to any of these questions, your asthma may not be under control. Call or see your doctor about your asthma.


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