How common is hemophilia

There are actually two kinds of hemophilia although both of them are typically found more in men than women. Hemophilia A is the more common of the two of them having a ratio of 1 in 4000 men in the world. Hemophilia B is found in newborn b…

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The two major forms of hemophilia occur much more commonly in males than in females. Hemophilia A is the most common type of the condition; 1 in 4,000 to 1 in 5,000 males worldwide are born with this disorder. Hemophilia B occurs in approxi…

http://ghr.nlm.nih.gov/condition%3Dhemophilia

According to my research haemophilia is not that common but if any one has it in any lineage it is passed and thereby becomes common in that lineage.

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Related Questions Answered on Y!Answers

How common is hemophilia and what is the fatality rate?

Q:

A: it depends on the type of hemophiliaFrequencyUnited StatesThe annual incidence of hemophilia A in Europe and North America is approximately 1 case per 5000 male births. It is the most common X-linked genetic disease, and the second most common factor deficiency after von Willebrand disease (VWD). The incidence of hemophilia B is estimated to be approximately 1 case per 30,000 male births. In the United States, the prevalence of hemophilia A is 20.6 cases per 100,000 male individuals, with 60% of those having severe disease. The prevalence of hemophilia B is 5.3 cases per 100,000 male individuals, with 44% of those having severe disease.InternationalThe worldwide incidence of hemophilia A is approximately 1 case per 5000 male individuals, with approximately one third of affected individuals not having a family history. Hemophilia B occurs in 1 case per 25,000 male individuals and represents one fourth to one fifth of all patients with hemophilia. The prevalence of hemophilia A varies with the reporting country, with a range of 5.4-14.5 cases per 100,000 male individuals. The prevalence of hemophilia B varies from 0.9-3.2 cases per 100,000 male individuals.Mortality/MorbidityBefore the widespread use of replacement therapy, patients with severe hemophilia had a shortened lifespan and diminished quality of life that was greatly affected by hemophilic arthropathy. Home therapy for hemarthroses became possible with factor concentrates. Prophylactic therapies with lyophilized concentrates that eliminate bleeding episodes help prevent joint deterioration, especially when instituted early in life (ie, at age 1-2 y). Life expectancy has increased from 11 years before the 1960s for patients who were severely affected to older than 50-60 years by the early 1980s.1Overall, the mortality rate for patients with hemophilia is twice that of the healthy male population. For severe hemophilia, the rate is increased 4-6 times. If hepatitis and cirrhosis are excluded, the overall mortality rate of patients with severe hemophilia A is 1.2 times that of the healthy male population.2, 3 * Viral complications became a problem during the replacement era. o The most serious of these was HIV infection. The first deaths of people with hemophilia due to AIDS were observed in the early 1980s. Rates of seroconversion were more than 75% for severe disease, 46% for moderate disease, and 25% for mild disease. In severe hemophilia B, seroconversion was observed at a rate of 46%. More than 50% of patients with hemophilia were infected with HIV by 1983. o In the United States, death rates of patients with hemophilia increased from 0.4 deaths per million population in 1979-1981 to 1.2 deaths per million population in 1987-1989; AIDS accounted for 55% of all hemophilia deaths. Causes of death shifted from intracranial and other bleeding to AIDS and cirrhosis from hepatitis. o The most common cause of death in patients with severe hemophilia is AIDS. * Life-threatening hemorrhage is also a significant problem. o Intracranial hemorrhage is a life-threatening hemorrhage with a lifetime risk of 2-8%, accounting for one third of deaths due to hemorrhage. o Other life-threatening hemorrhages include soft-tissue hemorrhages that obstruct airways or damage the internal organs. The life expectancy of patients with inhibitors is only slightly higher than the life expectancy of people without inhibitors. Fewer patients with inhibitors than patients without inhibitors have seroconversion for HIV. o Intracranial hemorrhage is the second most common cause of death and the most common cause of death related to hemorrhage. Of patients with severe hemophilia, 10% have intracranial bleeding, with a mortality rate of 30%.

Why is hemophilia more common in males than in females?

Q: Also:How does sickle-cell trait differ from sickle-cell disease?What are the 2 types ofn selective breeding, and how do they compare?

A: The gene for the most well known type of hemophilia is carried in humans on the X chromosome. Each X has a copy of the gene for hemophilia. Since males are XY and females are XX, males only get one type of copy of the gene. If it’s a bad copy, they have no second chance. Females on the other hand get 2 chances with this one. If they get one bad copy and one good copy, the good copy covers for the bad one. They have to have 2 bad copies of the gene to have hemophilia.I think sickle-cell is similiar, but in this case a good copy can’t cover as well for the bad copy.Sickle Cell Trait Versus AnemiaThe condition called sickle cell trait is different from sickle cell anemia. A person with sickle cell trait does not have the disease but carries the gene that causes the disease. People with sickle cell trait can pass the gene on when they have children. For more information on sickle cell trait, see the section on What Causes Sickle Cell Anemia.

How common is the disease Hemophilia?

Q: I know that hemophilia is a disease when someone has an alteration in one of the clotting factor genes, but how common is this disease?I don’t have it, but a family member of mines does& I just want to knowthank youuuuuuuuuuand is there any specific gender, ethnicity, or age that is affected more than others?

A: It affects about 1 in 10,000 people. I don’t know about ethnicity but it is much more common in men than in women. Also it is a condition that you are born with.