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What is the disorder were your blood cannot clot

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A:Hemophilia is rare,typically inherited,bleeding disorder that ranges from mild to severe ChaCha [ Source: http://www.chacha.com/question/what-is-the-disorder-were-your-blood-cannot-clot ]
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What is the disorder were your blood cannot clot
Hemophilia is rare,typically inherited,bleeding disorder that ranges from mild to severe ChaCha
Why do patients with liver diseases commonly develop blood clotti…?
Liver disorders can sometimes cause bleeding problems as your liver makes most of the clotting factors.
What Causes Blood Clotting Disorders?
A blood clotting disorder is a result of the body making either too many blood clotting factors or too few anti-clotting factors that limit clot formation. Excessive blood clotting may be caused by genetic disorders which are inherited from…

Related Questions Answered on Y!Answers

I would like to know if anyone out there has been on Coumadin/Lovenox therapy for treatment of a mild stroke?
Q: I was 6 weeks post-partum when I found out after having a stroke that I have a blood disorder in which the antibodies in the blood tend to clot my blood (Lupus-anticoagulant). I have been on Coumadin/Lovenox therapy for 1 1/2 months now and cannot reach a recommended PT/INR level between 2 and 3. Until my weekly pricks to check these levels is at this number, I must continue the Lovenox injections as a safety precaution because the Coumadin is not working well. I am now taking 12.5 mg ( I was on 10mg) a day. I guess you can say I’m frustrated because when I initially started this therapy I was told that I should be at the recommended level in about a week . Now at 1 1/2 months later I feel like a guinea pig trying a high dose(not helping) so now a higher dose (let’s see how your body accepts it at this dose). I’ve kept up with the diet guidelines and really feel this is not the problem.If anyone knows about what I’m talking about please respond.
A: Yes, and I have Antiphospholipid Antibody Syndrome (APS). The same disease that you have. You may be Coumadin resistent. But also there is a lot of information that the finger prick machines are not accruate for APS patients. They all carry disclaimers on them. So you may want your doctor to do a vein draw to compare them. Are you seeing a hematologist? They may want to do a Factor X essay and compare that to your INR/PT Typically most patients are kept at an INR of 3-4 with this disease. My INRs are hard to regulate. That is just part of APS. And since you are a woman, our hormones also play a role. Actaully, in the post partum period with the disease you are at some of the highest risk of clotting of than the pregnancy itself.Here is a wonderful beginners guide to APS: http://www.apsfa.org/newlydx.htm. Here is some basic information on APS: http://www.apsfa.org/aps.htmMy INR is kept at 3.5-4.5 plus I take aspirin because APS can cause both venous and arterial clotting. I am also on Plaquenil. Do you keep a INR log book and medical symptoms journal? It is amazing the patterns we can find. There is a non-profit organization in the US that can help you. There name is APS Foundation of America, Inc. Their link is below.Good Luck!
Hemophilia and Thrombophilia?
Q: Ah well I was wondering if there were any other people out there going through the same thing I am. My son was diagnosed with hemophilia when he was born. It was the first we had heard of it. We manage it from home and do great with it. I am very well informed and feel very comfortable controlling his bleeding episodes. The hospital we go to is fantastic. Now here is my concern. This is new for me. I found out two days ago that I also have a bleeding disorder called Factor Five Leiden aka Thrombosis or Thrombophilia. My son’s hospital and doctor handles all this stuff thankfully but they are having a meeting to discuss this with other doctors and won’t get back to me until next Thursday. I was informed I was very lucky to carry two pregnancies to term and this very much explains why we kept having miscarriages and why we only have two children after 9 years of trying to have more. We only had two children in the 9 year time frame. I have had several miscarriages and my new doctor decided to test me to find out if I was FVL positive. It turns out I was. (FVL- Factor Five Leiden).This does answer our questions as to why we kept having miscarriages when we’re trying for just ONE MORE child. Anyhow the hemophilia center (HTC) said that this may cause complications for us carrying another child again because my OB GYN wants to put me on heparin therapy and shots along side with baby aspirin if we get pregnant again to help prevent future blood clots in both myself and the fetus. But the problem is I also carry the hemophilia gene. If I carry another child that is hemophiliac I cannot take heparin therapy or so they say. I was wondering if there is another mother or parent out there that had to go through this before and what the outcome for them was? How did you manage your pregnancy with blood thinners and carry a hemophiliac at the same time? What were the results of the baby was he or she okay?More info about hemophilia and thrombophilia (FVL)-Hemophilia is a bleeding disorder where the child usually a male is missing a clotting factor, factor 8. And has to have infusions whether it be daily or weekly or every other day to control bleeding episodes. There is no cure for hemophilia it can only be controlled although bleeds so sneak out every now and then past the medication. Thrombophilia is the opposite of hemophilia, what I was told. Thrombophilia is still new to me seeing as I just found out about this two days ago when my labs came back. I was told thrombophilia is a bleeding disorder-factor five defincincy- where the person clots too much and is at risk for blood clots which can be fatal if not managed properly.
A: Your doctors are correct in saying that you are lucky to have not had blood clots. If you are Factor V Leiden homozygous, I would consider it a miracle. If you are heterozygous, I will tell you that many women who have this disorder will go their entire life without ONE problem and may never know it’s a problem. This Factor V mutation is very common and makes you about 5 times more likely to have a blood clot. Obviously being pregnant makes you even more likely to have a clot, and FVL is known to cause you to lose your baby late in the pregnancy.I know your doctors tried to explain it to you, but… basically the formation of a blood clot is just a long series of steps. Every step requires a different protein called Factors. At the same time, there are other chemicals which either speed up or slow down the system. These chemicals (call them cofactors) come in and either turn the “switch” on your Factor V protein on (speeding up the formation of a clot) or off (slowing down the formation). If you are heterozygous, half of your Factor V proteins have a mutation right at that switch, so the cofactors can’t turn off the switch. So in order to prevent you from forming an unnecessary blood clot, all other factors have to do their jobs perfectly to stop or slow down the clot. If your disorder is not managed properly, a clot is most likely to form in the deep veins of your legs (called deep vein thrombosis or DVT). This *could* cause pain and swelling, or you could have no symptoms at all like I did when I was 21. If the clot does not dissolve quickly, it can break free from your vein wall and travel. Now it’s called an embolus. The embolus can go to your heart and if it’s big enough cause a heart attack. If it travels through your heart, it will end up in the tiny capillaries in your lungs. This is what happened to me. This you WILL feel, it will hurt and you’ll likely be short of breath. 30% of patients with a pulmonary embolism die, 25% die instantly. Personally, I had multiple emboli in both of my lungs. My doctors were surprised I was still alive when I walked into the ER. So there’s your crash course in blood clotting disorders! as for your main question:So I did some research which confirmed my first thought which was heparin does not cross the placenta. When you are on heparin or warfarin therapy, your target INR (which is a ratio of the time it takes for your blood to clot vs the time it takes for a normal person’s blood to clot) is usually between 2-3. In other words, the heparin makes your blood take 2 to 3 times longer than it takes a “healthy” person’s blood. If that were transferred to the baby, I believe it would be catastrophic even if he/she were completely healthy. Heparin is approved for pregant women simply because it does not cross the placenta and has no connection to birth defects as the pill form of warfarin (or Coumadin) does!Which doctor told you that you could not take heparin if you were carrying a child with hemophilia? I suggest you get a second opinion on this matter, especially if it were your OBGYN who told you so. Your information on this should come only from a hematologist as bleeding disorders are their specialty. I hate to offer this option, but hemophilia is detectable early in pregnancy at which point you could decide to discontinue the pregnancy. Definitely do not refuse the heparin during the pregnancy, you could both die. Finally, there are a few websites that have helped me gain the knowledge and even the strength when times were tough and I was feeling sorry for myself:stoptheclot.orgfvleiden.orgdailystrength.orgThe first two have a lot of info and also a place you can ask a specialists any questions you have. Daily Strength is a free website much like Y!A. The DVT forum isn’t very active, but the Pulmonary Embolism one is. There are a lot of nice people on there that have a lot more knowledge than I do! Even tho you haven’t had a PE, they would be willing to answer any more questions you have and also offer encouragement! I’m sorry this was so long, but I hope I’ve helped. Good luck with everything, and feel free to email me again if you need anymore help!
Please help me with my Biology!?
Q: 1. Humans have 23 pairs of sex chromosomes and 1 pair of autosomes 23 pairs of chromosomes, of which 1 pair are sex chromosomes 22 pairs of sex chromosomes and 1 pair of autosomes 1 pair of sex chromosomes and 12 pair of autosomes2. A female is created with the fertilization of an egg with a Y chromosome by a sperm with a X chromosome an egg with an X chromosome by a sperm with an Y chromosome an egg with a Y chromosome by a sperm with a Y chromosome an egg with an X chromosome by a sperm with an X chromosome3. Genes found on the X chromosome are considered sex-linked sex-limited sex-influenced autosomal recessive4. Which of the following is a sex-linked trait? sickle-cell anemia dwarfism albinism color blindness5. If a male with hemophilia is crossed with a carrier female, what is the probability their children will have hemophilia? 25 percent 50 percent 75 percent 100 percent6. Sex-influenced is defined as your gender is more influential in society your gender determines if the heterozygote will express the trait your gender is not able to get the genetic disorder having an X and Y chromosome7. Nondisjunction is the pulling apart of chromosomes during mitosis and meiosis a chromosome that has been broken when chromosomes cannot replicate in interphase the unequal separation of chromosomes during meiosis8. What is the end result of a cell that underwent nondisjunction? cells with more and less chromosomes than they should have a fertilized egg with an extra chromosome a sperm cell with one less chromosome mutated cells9. Trisomy 21 is commonly called Down syndrome Patau’s syndrome Edwards syndrome Turner’s syndrome10. Which of the following genetic conditions describes Turner’s syndrome? an extra X compared to a normal female XXY sex chromosomes instead of XX or XY only one X for sex chromosomes three of the thirteenth chromosome11. What is the probability that parents with type AB and type O blood will have offspring with type O blood? 75 percent 50 percent 25 percent 0 percent12. Which of the following children cannot be born from the following cross: AO x AB? type A type AB type B type O13. A mother has type AB blood, and the father has type A, and they have five children with the following blood types: A, AB, B, A, B; what is the genotype of the father? AA AO BB BO AB14. Which of the following genes is a good example of multiple alleles? blood types colorblindness Huntington’s disease Rh factor15. When using a pedigree, males are drawn as what shape? circle triangle square rectangle pentagon16. How many autosomes does a person have in each cell of his or her body? 23 pairs 22 pairs 1 pair 20 pairs17. Which of the following statements about sex-linked disorders is true? It is easier for women to express a sex-linked disorder. Prostate cancer is a good example of a sex-linked disorder. Balding is a good example of a sex-linked disorder. It is easier for men to express a sex-linked disorder.18. What sex chromosomes does a person with Klienfelter’s Syndrome have? XXX XO XXY XY19. What does a person with hemophilia lack? the ability to see the blue-green color spectrum the ability of their blood to clot an X chromosome the Rh factor20. Which of the following conditions is not an example of nondisjunction? Huntington’s disease Turner’s Syndrome Klienfelter’s Syndrome Trisomy 21
A: For 5, you might want to know a bit more how it works.Haemophilia is on the X chromosone and is recessive, this means a Male haemophiliac can not give Haemophilia to his sons, but all daughters he has will be carriers. A carrier can pass it on to either their daughter/son but this is only 50% chance.If its a daughter it’ll be 100% (only carrier though), if it’s a son it’ll be 50%. For your question, the answer is 50%.
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