What are three ways mutations can occur in genes involved in cell-cycle regulations

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Mutations in the gene that codes for the p53 protein represent the most common genetic malfunction in human cancers and are present in more than half of all cases of the disease. Apparently, these genetic mutations [ Source: http://www.chacha.com/question/what-are-three-ways-mutations-can-occur-in-genes-involved-in-cell%26%2345%3Bcycle-regulations ]
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What are three ways mutations can occur in genes involved in cell…?
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Mutations in the gene that codes for the p53 protein represent the most common genetic malfunction in human cancers and are present in more than half of all cases of the disease. Apparently, these genetic mutations
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